Publikacje
2023
- Haider H. Dar, K. Mikulska-Rumińska, Yulia Y. Tyurina, Diane K. Luci, Adam Yasgar, Svetlana N. Samovich, Alexander A. Kapralov, Austin B. Souryavong, Vladimir A. Tyurin, Andrew A. Amoscato, Michael W. Epperly, Galina V. Shurin, Melissa Standley, Theodore R. Holman, Claudette M. St. Croix, Simon C. Watkins, Andrew P. VanDemark, Sandeep Rana, Alexey V. Zakharov, Anton Simeonov, Juan Marugan, Rama K. Mallampalli, Sally E. Wenzel, Joel S. Greenberger, Ganesha Rai, Hülya Bayir, Ivet Bahar, Valerian E. Kagan,
"Discovering selective antiferroptotic inhibitors of the 15LOX/PEBP1 complex noninterfering with biosynthesis of lipid mediators"
PNAS 120 (2023), e221889612
DOI: 10.1073/pnas.2218896120 - A.A. Amoscato, T. Anthonymuthu, O. Kapralov, L.J. Sparvero, I.H. Shrivastava, K. Mikulska-Rumińska, V.A. Tyurin, A.A. Shvedova, Y.Y. Tyurina, I. Bahar, S. Wenzel, H. Bayir, V.E. Kagan,
"Formation of protein adducts with Hydroperoxy-PE electrophilic cleavage products during ferroptosis"
Redox Biol. 63 (2023), 102758
DOI: 10.1016/j.redox.2023.102758
2021
- K. Mikulska-Rumińska, Tamil S Anthonymuthu, Anastasia Levkina, Indira H Shrivastava, Aleksandr A Kapralov, Hülya Bayır, Valerian E Kagan, Ivet Bahar,
"NO● Represses the Oxygenation of Arachidonoyl PE by 15LOX/PEBP1: Mechanism and Role in Ferroptosis "
Int. J. Mol. Sci. 22 (2021), 5253
DOI: 10.3390/ijms22105253 - W. Sun, V. Tyurin, K. Mikulska-Rumińska, I. Shrivastava, T. Anthonymuthu, Y. Zhai, M. Pan, H. Gong, D. Lu, J. Sun, W. Duan, S. Korelov, A. Abramov, P. Angelova, I. Miller, O. Baharier, G. Mao, H. Dar, A. Kapralov, A. Amoscato, T. Hastings, T. Greenamyre, C. Chu, Y. Sadovsky, I. Bahar, H. Bayir, Y. Tyurina, R. He, V. Kagan,
"Phospholipase iPLA2β averts ferroptosis by eliminating a redox lipid death signal"
Nat. Chem. Biol. 17 (2021), 465-476
DOI: 10.1038/s41589-020-00734-x - She Zhang, James M Krieger, Yan Zhang, Cihan Kaya, Burak Kaynak, K. Mikulska-Rumińska, Pemra Doruker, Hongchun Li, Ivet Bahar,
"ProDy 2.0: Increased Scale and Scope after 10 Years of Protein Dynamics Modelling with Python"
Bioinf. Z (2021), X-Y
DOI: 10.1093/bioinformatics/btab187 - Jargalsaikhan Dagvadorj, K. Mikulska-Rumińska, Gantsetseg Tumurkhuu, Rojo A. Ratsimandresy, Jessica Carriere, Allen M. Andres, Stefanie Marek-Iannucci, Yang Song, Shuang Chen, Malcolm Lane, Andrea Dorfleutner, RobertaA. Gottlieb, Christian Stehlik, Suzanne Cassel, Fayyaz S. Sutterwala, Ivet Bahar, Timothy R. Crother, Moshe Arditi,
"Recruitment of pro-IL-1a to Mitochondrial Cardiolipin, via shared LC3 Binding Domain, Inhibits Mitophagy and Drives NLRP3 Activation"
PNAS 118 (2021), e201563211
DOI: 10.1073/pnas.2015632118 - T. Anthonymuthu, Y.Tyurina, W. Sun, K. Mikulska-Rumińska, I. Shrivastava, V. Tyurin, F. Cinemre, H. Dar, A. VanDemark, T. Holman, Y. Sadovsky, B. Stockwell, R. He, I. Bahar, H. Bayır, V. Kagan,
"Resolving the paradox of ferroptotic cell death: ferrostatin-1 binds to 15LOX/PEBP1 complex, suppresses generation of peroxidized ETE-PE, and protects against ferroptosis"
Redox Biol. 38 (2021), 101744
DOI: 10.1016/j.redox.2020.101744 - Yan Zhang, James Krieger, K. Mikulska-Rumińska, Burak Kaynak, Carlos Oscar S Sorzano, José-María Carazo, Jianhua Xing, Ivet Bahar,
"State-dependent sequential allostery exhibited by chaperonin TRiC/CCT revealed by network analysis of Cryo-EM maps"
Prog. Biophys. Mol. Biol. 160 (2021), 104-120
DOI: 10.1016/j.pbiomolbio.2020.08.006
2020
- Eléonore Moreau, K. Mikulska-Rumińska, Mathilde Goulu, Stéphane Perrier, Caroline Deshayes, Maria Stankiewicz, Véronique Apaire-Marchais, W. Nowak, Bruno Lapied,
"Orthosteric muscarinic receptor activation by the insect repellent IR3535 opens new prospects in insecticide-based vector control"
Sci. Rep. 10 (2020), 1-15
DOI: 10.1038/s41598-020-63957-x - Alexandr Kapralov, Qin Yang, Haider Dar, Yulia Tyurina, Tamil Anthonymuthu, Rina Kim , Claudette Croix, K. Mikulska-Rumińska, Bing Liu, Indira Shrivastava, Vladimir Tyurin, Hsiu-Chi Ting, Yijen Wu, Yuan Gao, Galina Shurin, Margarita Artyukhova, Liubov Ponomareva, Peter Timashev, Rosario Domingues, Detcho Stoyanovsky, Jeol Greenberger, Rama Mallampalli, Ivet Bahar, Dmitry Gabrilovich, Hülya Bayır, Valerian Kagan,
"Redox lipid reprogramming commands susceptibility of macrophages and microglia to ferroptotic death"
Nat. Chem. Biol. 16 (2020), 278-290
2019
- K. Mikulska-Rumińska, Indira Shrivastava, James Krieger, She Zhang, Hongchun Li, Hülya Bayır, Sally Wenzel, Andrew VanDemark, Valerian Kagan, Ivet Bahar,
"Characterization of Differential Dynamics, Specificity, and Allostery of Lipoxygenase Family Members"
J. Chem. Inf. Model. 59 (2019), 2496-2508 - K. Mikulska-Rumińska, J. Strzelecki, W. Nowak,
"Dynamics, nanomechanics and signal transduction in reelin repeats"
Sci. Rep. 9 (2019), 1-13 - H. Dar, Y. Tyurina, K. Mikulska-Rumińska, I. Shrivastava, H. Ting, A. Tyurin, J. Krieger, C. Croix, S. Watkins, E. Bayir, G. Mao, C. Ambruster, A. Kapralov, H. Wang, M. Parsek, T. Anthonymuthu, A. Ogunsola, B. Flitter, C. Freedman, J. Gaston, T. Holman, J. Pilewski, J. Greenberger, R. Mallampalli, Y. Doi, J. Lee, I. Bahar, J. Bomberger, H. Bayır, V. Kagan,
"Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium"
J. Clin. Invest. 128 (2019), 4639-4653
DOI: https://doi.org/10.1172/JCI99490
2018
- Anthonymuthu, Tamil S, Kenny, Elizabeth M. , Shrivastava, Indira, Tyurina, Yulia Y, Hier, Zachary E. , Ting, Hsiu-Chi , Dar, Haider H , Tyurin, Vladimir A. , Nesterova, Anastasia , Amoscato, Andrew A. , K. Mikulska-Rumińska, Rosenbaum, Joel C. , Mao, Gaowei, Zhao, Jinming, Conrad, Marcus , Kellum, John A. , Wenzel, Sally E. , VanDemark, Andrew P. , Bahar, Ivet , Kagan, Valerian E., Bayir, Hülya ,
"Empowerment of 15-Lipoxygenase Catalytic Competence in Selective Oxidation of Membrane ETE-PE to Ferroptotic Death Signals, HpETE-PE"
J. Am. Chem. Soc. 140 (2018), 17835-17839
2017
- K. Mikulska-Rumińska, A. J. Kulik, C. Benadiba, I. Bahar, G. Dietler, W. Nowak,
"Nanomechanics of multidomain neuronal cell adhesion protein contactin revealed by single molecule AFM and SMD"
Sci. Rep. 7 (2017), 1-11
DOI: 10.1038/s41598-017-09482 - S.E. Wenzel, Y.Y. Tyurina, J. Zhao, C.M. St. Croix, H.H. Dar, G. Mao, V.A. Tyurin, T.S. Anthonymuthu, A.A. Kapralov, A.A. Amoscato, K. Mikulska-Rumińska, I.H. Shrivastava, E.M. Kenny, Q. Yang, J.C. Rosenbaum, L.J. Sparvero, D.R. Emlet, X. Wen, Y. Minami, F. Qu, S.C. Watkins, T.R. Holman, A.P. van Demark, J.A. Kellum, I. Bahar, H. Bayir, V.A. Kagan,
"PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals"
Cell 171 (2017), 628-641
2015
- Aly Abd-Ella, Maria Stankiewicz, K. Mikulska-Rumińska, W. Nowak, Cédric Pennetier, Mathilde Goulu, Carole Fruchart-Gaillard, Patricia Licznar, Véronique Apaire-Marchais, Olivier List, Vincent Corbel, Denis Servent, Bruno Lapied,
"The Repellent DEET Potentiates Carbamate Effects via Insect Muscarinic Receptor Interactions: An Alternative Strategy to Control Insect Vector-Borne Diseases"
PLOS ONE 10(5) (2015), e0126406-+20
DOI: DOI:10.1371/journal.pone.0126406
2014
- K. Mikulska-Rumińska, J. Strzelecki, W. Nowak,
"Nanomechanics of β-rich proteins related to neuronal disorders studied by AFM, all-atom and coarse-grained MD methods"
J. Mol. Model. 20 (2014), 2144-2153
DOI: DOI: 10.1007/s00894-014-2144-5
2013
- K. Mikulska-Rumińska, W. Nowak,
"Nanomechanics of proteins related to autism spectrum disorder"
Eur. Biophys. J. Biophys. Lett. Suppl. 42 (Suppl 1) (2013), S94
DOI: DOI 10.1007/s00249-013-0917-x - K. Mikulska-Rumińska, R. Jakubowski, Ł. Pepłowski, M. Dąbrowski, A. Gogolińska, Włodzisław Duch, W. Nowak,
"On applications of virtual atomic force microscope in studies of brain proteins"
Eur. Biophys. J. Biophys. Lett. Suppl. 42 (Suppl 1) (2013), S93-S93
DOI: DOI 10.1007/s00249-013-0917-x
2012
- J. Strzelecki, M. Dąbrowski, dr Strzelecka Joanna, dr Tszydel Mariusz, K. Mikulska-Rumińska, W. Nowak, A. Balter,
"AFM Investigation of Biological Nanostructures"
Acta Phys. Pol. A 122 (2012), 329-332 - A. Jasiński, K. Mikulska-Rumińska, B. Krajnik, S. Maćkowski, W. Nowak,
"Dynamics of Protein Elements of Hybrid Nanostructures - Molecular Dynamics Simulations of Light Harvesting Peridinin-Chlorophyll a-Protein Model "
Acta Phys. Pol. A 122 (2012), 284-288 - K. Mikulska-Rumińska, J. Strzelecki, A. Balter, W. Nowak,
"Nanomechanical unfolding of α-neurexin - a major component of the synaptic junction"
Chem. Phys. Lett. 521 (2012), 134-137
DOI: 10.1016/j.cplett.2011.11.033
2011
- K. Mikulska-Rumińska, Ł. Pepłowski, W. Nowak,
"Nanomechanics of Ig-like domains of human contactin (BIG-2)"
J. Mol. Model. 17 (2011), 2313-2323
DOI: 10.1007/s00894-011-1010-y - K. Mikulska-Rumińska, J. Strzelecki, A. Balter, W. Nowak,
"Nanomechanics of neuronal junction – stretching FNIII domains of human contactins"
Eur. Biophys. J. Biophys. Lett 40 (2011), S220-S220
DOI: 10.1007/s00249-011-0729-9 - J. Strzelecki, J. Strzelecka, K. Mikulska-Rumińska, M.Tszydel, A. Balter, W. Nowak,
"Nanomechanics of new materials - AFM and computer modelling studies of trichoptera silk"
Cent. Eur. J. Phys. 9 (2) (2011), 482-491
2010
- K. Mikulska-Rumińska, D. Rumiński,
"Fizyka w szkole nie musi być nudna"
Wychowanie na co dzień 4-5 (2010), I-VI
2009
- J. Strzelecki, K. Mikulska-Rumińska, Małgorzata Lekka, Andrzej Kulik, A. Balter, W. Nowak,
"AFM force spectroscopy and steered molecular dynamics simulation of protein Contactin 4"
Acta Phys. Pol. A Suppl. 116 (2009), 156-159 - J. Strzelecki, K. Mikulska-Rumińska, A. Balter, W. Nowak,
"Single molecule AFM force spectroscopy and steered molecular dynamics of Contactin-4 protein"
Eur. Biophys. J. Biophys. Lett. Suppl. 38 (Suppl 1) (2009), S117-S117
English version
